The Shackelford lab is located in the heart of UCLA’s David Geffen School of Medicine in Los Angeles. We study the intersection of signal transduction and metabolism in cancer in order to identify the molecular and metabolic basis of tumorigenesis. To more accurately study cancer metabolism in the context of the tumor environment we employ a range of technologies that include PET imaging, microscopy, mass spectrometry and biochemistry that allows us to visually and functionally profile tumors as they progress and evolve during tumorigenesis. We integrate both basic and translational research platforms in order to develop more effective strategies to improve detection, diagnosis and treatment for cancer patients....
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